Two sample MR report
CD52_Dendritic Cell (DC) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.2512229 | 0.3072220 | 0.4734175 |
| Weighted median | 5 | 0.0810849 | 0.0215240 | 0.0001651 |
| Inverse variance weighted | 5 | 0.0596763 | 0.0285446 | 0.0365612 |
| Simple mode | 5 | 0.0842465 | 0.0228576 | 0.0210981 |
| Weighted mode | 5 | 0.0842465 | 0.0214681 | 0.0171859 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 12.13552 | 3 | 0.0069331 |
| Inverse variance weighted | 13.72415 | 4 | 0.0082295 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0816299 | 0.1302584 | 0.5753177 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 8.16e-05 | 0 | TRUE | 0.3963143 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
